IMHS - Molecular Health Sciences Platform

Prof. Dr. Markus Stoffel

Markus Stoffel

ETH Zürich
Prof. Dr. Markus Stoffel
Inst. f. Molecular Health Sciences
HPL H 36
Otto-Stern-Weg 7
8093 Zuerich

Phone: +41 44 633 45 60
Fax: +41 44 633 13 62

Metabolism & Metabolic Diseases

Integration of extracellular hormonal and nutrient signals into comprehensive gene expression patterns leads to tightly choreographed phenotypic responses that regulate metabolism and cellular differentiation. My overall research interest is to elucidate the fundamental molecular mechanisms that regulate glucose and lipid metabolismthrough the study of transcriptional and translational regulators that control energy homeostasis in response to physiological (i.e. fasting) and environmental (i.e. caloric excess) stress. Our work focuses on understanding transcriptional and microRNA regulatory networks and their interactions in pancreatic b-cells, liver, fat and hypothalamus. The importance of genetic/genomic regulation in the maintenance of glucose and lipid homeostasis is underscored by the many examples of aberrant signal transduction and transcriptional activation resulting in obesity and type 2 diabetes and thedevelopment of secondary complications.

Administrative Assistant

Silvia Pfister


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