Publication: Vector Integration Sites Identification for Gene-Trap Screening in Mammalian Haploid Cells.

20.03.2017

Forward genetic screens using retroviral gene-trap vectors in a haploid genome revolutionized the investigation of molecular networks in mammals. The analysis of human and mouse haploid screens allowed the authors Yu and Ciaudo to describe PhiT-seq data and to define quality control steps. Integration of transcriptomic data improved the performance of candidate gene identification. Finally, the authors developed: VISITs, a dedicated pipeline for analyzing PhiT-seq data.

 
 
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Sun Apr 30 12:53:36 CEST 2017
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