Publications

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Lyons, G. E., Muhlebach, S., Moser, A., Masood, R., Paterson, B., Buckingham, M. E., and Perriard, J. C. (1991). Developmental regulation of creatine kinase expression by myogenic factors in embryonic mouse and chick skeletal muscle. Development, 113, 1017-1029.

Billeter, R., Messerli, M., Wey, E., Puntschart, A., Jostarnd, K., Eppenberger, H. M., and Perriard, J. C. (1992). Fast Myosin Light Chain Expression in Chicken Skeletal Muscles Studied by "in situ" Hybridization. J. Histochem. Cytochem., 40, 1547-1557.

Perriard, J. C., von Arx, P., Bantle, S., Eppenberger, H. M., Eppenberger-Eberhardt, M., Messerli, M., and Soldati, T. (1992). Molecular analysis of protein sorting during biognesis of muscle cytoarchitecture. In: A. El Haj (Ed.), Molecular Biology of Muscle (pp. 219-235). Cambridge, UK.: Society for Developmental Biology.

Messerli, M., van der Voort, H. T. M., Rungger-Brandle, E., and Perriard, J.-C. (1993). Three-Dimensional Visualization of Multi-Channel Volume Data: The amSFP Algorithm. Cytometry, 14, 725-735. Messerli, J.M., Eppenberger, M.E., Rutishauser, B., Schwarb,P., Eppenberger, H.M., and Perriard, J.-C. (1993). Remodeling of Cardiomyocyte Cytoarchiteture Visualized by 3D Confocal Microscopy. Histochemistry, 100, 193-202.

Perriard, JC: (1993). Myomesin and M-protein. In Kreis.T., Vale R, eds. Guidebook to the Cytoskeletal and Motor Proteins. Oxford, Oxford University Press, pp. 58-59. Perriard, JC: (1993). Sarcomeric MM-creatine kinase. In Kreis.T., Vale R, eds. Guidebook to the Cytoskeletal and Motor Proteins. Oxford, Oxford University Press, pp. 71-72.

Muhlebach, S.M., Gross, M.,Wirz, T., Wallimann, T., Perriard, J.-C., and Wyss, M. (1994). Sequence homology and structure predictions of the creatine kinase isoenzymes. Mol. Cell. Biochem.133/134, 245-262.

Messerli, M., and J.-C., Perriard. (1995). Three dimensional analysis and visualization of myofibrillogenesis in adult cardiomyocytes by confocal microscopy. Microscopy Res. & Tech., 30., 521-530.

Kraft, T., Messerli, M., Rutishauser, B., Perriard, J.-C., Wallimann, T., and Brenner, B. (1995). Equilibration and exchange of fluorescently labelled molecules in skinned skeletal muscle fibers observed by confocal microscopy. Biophysical J., 69, 1246-1258.

von Arx, P., Bantle, S., Soldati, T., and Perriard, J.-C.(1995). Dominant Negative Effect of Cytoplasmic Actin Isoproteins on Cardiomyocyte Cytoarchitecture and Function. J. Cell Biol.131, 1759-1773.

Muhlebach, S.M., Wirz, T., Brandle, U., and Perriard, J.-C. (1996). Evolution of CK genes and their expression in chicken tissues and embryonic development. J.Biol. Chem. 271, 11920-11929.

Komiyama, M., Soldati, T., von Arx, P., and Perriard, J.-C. (1996). The intracompartmental sorting of myosin alkali light chain isoporteins reflects the sequence of developmental expression as determined by double epitope-tagging competition. J. Cell Sci. 109, 2089-2099

Bantle, S.,Keller, S., Haussmann, I., Auerbach, D., Perriard, E., Muhlebach, S., and Perriard, J.-C. (1996). Tissue specific isoforms of chicken myomesin are generated by alternative splicing. J. Biol. Chem. 271, 19042-19052

Arber, S., Hunter, J. J., Ross, J. J., Hongo, M., Sansig, G., Borg, J., Perriard, J.-C., Chien, K. R. and Caroni, P. (1997). MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, and heart failure. Cell, 88, 393-403.

Auerbach, D., Rothen-Rutishauser, B., Bantle, S., Leu, M., Ehler, E., Helfman, D. and Perriard, J.-C. (1997). Molecular mechanisms of myofibril assembly in heart. Cell Struct. Function, 22, 139-146.

Becker, K. D., Gottshall, K. R., Hickey, R., Perriard, J.-C. and Chien, K. R. (1997). Point mutations in human b-cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: An ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutatation display normal assembly. J. Cell Biol., 137, 131-140.

Bohner, V., Langguth, P., Ottiger, C., Wunderli-Allenspach, H., Rognan, D., Rothen-Rutishauser, B., Perriard, J.-C., Lang, S., Biber, J. and Merkle, H. P. (1997). Structure-permeation relations of Met-enkephalin peptide analogues on absorption and secretion mechanisms in Caco-2 monolayers. J. Pharm. Sci., 86, 846-853.

Mounier, N., Perriard, J.-C., Gabbiani, G., and Chaponnier, C. (1997). Transfected muscle and non-muscle actins are differentially sorted by cultured smooth muscle and non-muscle cells. J. Cell Science, 110, 839-846.

Rothen-Rutishauser, B., Ehler, E., Perriard, E., Messerli, M. and Perriard, J.-C. (1998). Different behaviour of the non-sarcomeric cytoskeleton in neonatal and adult rat cardiomyocytes. J. Mol. Cell. Cardiol. 30, 19-31.

Götz, J., Probst, A., Ehler, E., Hemmings, B. and Kues, W. (1998). Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Ca. Proc. Natl. Acad. Sci. USA 95, 12370-12375.

Helfman, D. M., Berthier, C., Grossman, J., Leu, M., Ehler, E., Perriard E. and Perriard, J.-C. (1999). Nonmuscle tropomyosin-4 requires coexpression with other low molecular weight isoforms for binding to thin filaments in cardiomyocytes. J. Cell Sci. 112, 371-380.

Ehler, E., Rothen, B.M., Hämmerle, S.P., Komiyama, M. and Perriard, J.-C. (1999). Myofibrillogenesis in the developing chicken heart: Assembly of Z-disk, M-line and the thick filaments. J. Cell Sci. 112, 1529-1539.

Ehler, E. and Perriard J.-C. (2000). Cardiomyocyte cytoskeleton and myofibrillogenesis in healthy and diseased heart. Heart Failure Reviews 5, 259-269

Ferrari, A., Ehler, E., Nitsch, R.M. and Götz, J. (2000). Immature human NT2 cells grafted into mouse brain differentiate into neuronal and glial cell types. FEBS Lett., 486, 121-125

Ehler, E., Horowits, R., Zuppinger, C., Price, R.L., Perriard, E., Leu, M., Caroni, P., Sussman, M., Eppenberger, H.M. and Perriard, J.-C. (2001). Alterations at the intercalated disk associated with the absence of muscle LIM protein. J. Cell Biol. 153, 763-772

Potthast, R., Ehler, E., Scheving, L.A., Sindic, A., Schlatter, E. and Kuhn, M. (2001). High salt intake increases uroguanylin expression in mouse kidney. Endocrinology, 14, 3087-3097

Young, P., Ehler, E. and Gautel, M. (2001). Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly. J. Cell Biol., 154, 123-136

Leu, M., Ehler , E. and Perriard, J.-C. (2001): Characterization of postnatal growth of the murine heart . Anat. Embryol 204, 217-224

Magyar, J.P., Nemir, M. , Ehler, E. , Suter, N. , Perriard, J-C. andEppenberger H.M. (2001): Mass production of embryoid bodies in microbeads. Ann. NY Acad. Sci. 944, 135-143

Ehler, E. and Perriard, J.-C. (2001): Emergence of the first myofibrils and targeting mechanisms directing sarcomere assembly in developing cardiomyocytes. In "Myofibrillogenesis (ed. D. K. Dube), Birkhäuser, Boston, Basel, Berlin 2001, 41-58

Dätwyler, D.A., Magyar, J.P., Busceti, V., Hirschy, A., Perriard, J.-C., Bailey, J.E. and Eppenberger, H.M. (2001): Recombinant Sindbis virus allows expression and precise targeting of proteins of the contractile apparatus in cultured cardiomyocytes. Basic Res Cardiol 96, 630-635

Ehrengruber, M.U., E. Ehler, M.A. Billeter, and H.Y. Naim. 2002. Measles virus spreads in rat hippocampal neurons by cell-to-cell contact and in a polarized fashion. J Virol. 76:5720-8.

Fielitz, J., A. Dendorfer, R. Pregla, E. Ehler, H.R. Zurbrugg, J. Bartunek, R. Hetzer, and V. Regitz-Zagrosek. 2002. Neutral endopeptidase is activated in cardiomyocytes in human aortic valve stenosis and heart failure. Circulation. 105:286-289.

Kuhn, M., R. Holtwick, H.A. Baba, J.C. Perriard, W. Schmitz, and E. Ehler. 2002. Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice. Heart. 87:368-74.

 
 
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